Table 3.
Treatment compliance and duration
| Resection |
N Total Days, mean ± SD |
|---|---|
| Interval from diagnosis to resection | 10 ± 15.2 |
| Resection compliance | 30 (100%) |
| Grade of resection | |
| Complete | 15 (50.0%) |
| Partial | 8 (26.7%) |
| Biopsy | 0 (0.0%) |
| Data not available | 7 (23.3%) |
| Average percent of resection (in MRI) | 94.7% ± 12.4% |
| Radiochemotherapy | Number of patients; median days (% of total) |
| Interval from resection to radiochemotherapy | 53.0 ± 24 |
| Interval from radiochemotherapy to adjuvant chemotherapy | 48.0 ± 79 |
| Radiotherapy per protocol | 30 (100%) |
| Concomitant chemotherapy | |
| Less than 4 doses of vincristine (VCR) | 2 (6.6%) |
| 4–6 doses of VCR | 16 (53.3%) |
| 7–8 doses of VCR | 12 (40.0%) |
| Maintenance chemotherapy | Number of patients (% of total) |
| Interval from resection to adjuvant chemotherapy | 166 ± 76.5 |
| Dropout rate | |
| By cycle 1 | 5 (16.7%) |
| By cycle 2 | 5 (16.7%) |
| By cycle 3 | 9 (30.0%) |
| By cycle 4 | 9 (30.0%) |
| By cycle 5 | 9 (30.0%) |
| By cycle 6 | 11 (36.7%) |
| By cycle 7 | 17 (56.7%) |
| By cycle 8 | 20 (66.7%) |
| Cycles of chemotherapy given | 155 (100%) |
| Cycles given per protocol | 77 (49.7%) |
Note. Time to start of each treatment part was calculated from time of tumor resection to first day of the respective treatment. Extent of resection was calculated from postoperative MRI, and compliance to radiochemotherapy and maintenance chemotherapy was extracted. Data were calculated in the intent-to-treat population.