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Effects of pyridyl disulfides on CoASH and cellular redox state. (A) Mass spectroscopy revealed that S-(octylthio)-2-pyridine (1h) reacts with coenzyme A (CoASH) in situ by thiol-disulfide exchange. (B) Effect of disulfide 1h in S. aureus by nitroblue tetrazolium (NBT) staining. (C) Effect of disulfide 1h in S. aureus by dicholorodihydrofluorescin-diacetate (DCFH-DA) staining.
