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. 2018 Jan 1;11(1):dmm031302. doi: 10.1242/dmm.031302

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© 2018. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 4. — Histology of MCF7 tumors in P. californicus. (A) H&E (top) or trichrome (bottom)-stained sections of MCF7 tumors in P. californicus (magnification, 10×). (B) Comparison of H&E stained sections of MCF7 tumors treated with FLV, LTR or DMSO (magnification, 40×). (C) Estradiol levels in the plasma of eight P. californicus and five female SCID mice measured by ELISA (Cayman Chemical, MI). P values are indicated (Student's t-test). (D) Percentage of tumors growing in relation to the ratio of HFFF2 fibroblasts admixed with the MCF7 cells. Tumors were scored as positive when tumor volume reached at least 100 mm³ after 3 weeks.