Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 1;11(1):dmm031716. doi: 10.1242/dmm.031716

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Fig. 4. — Evaluation of AREG, EGFR, p-EGFR, p-AKT and p-mTOR expression in original tumor and GUMC220/221 CRC cultures, xenografts and Matrigel cultures. (A-D) Representative IHC images for AREG, EGFR, p-EGFR, p-AKT and p-mTOR in adjacent normal tissue (top) and MEC (cancer tissue, bottom) (A), GUMC220 (top) and GUMC221 (bottom) cell pellets from CRC cultures (B), GUMC220 (top) and GUMC221 (bottom) xenografts (C), and GUMC220 (top) and GUMC221 (bottom) Matrigel spheroids (D). Images were taken at 40× magnification. Scale bars: 10 μm. (E) Left y-axis: relative FPKM values for AREG, EGFR, AKT and mTOR in GUMC220 and GUMC221. *P<0.05 (Cuffdiff). Right y-axis: for reference, relative RPKM reads for AREG, EGFR, AKT and mTOR from the HPA for normal salivary gland tissue.