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. Author manuscript; available in PMC: 2018 Feb 19.
Published in final edited form as: Mol Reprod Dev. 2016 Aug;83(8):675–683. doi: 10.1002/mrd.22682

Figure 2. MT-nanotube mediated niche-stem cell signaling.

Figure 2

(A) Model for MT-nanotube mediated signaling. Dpp induces MT-nanotube formation, and receptor–ligand interaction occurs at the surface of MT-nanotubes, leading to signaling activation in GSCs. (B) Dpp-mCherry (red) expressed in hub cells together with GFP-α-Tubulin (green, hub cell cortex) using hub specific unpaired (Upd) promoter. DppmCherry forms punctae along hub cell cortex (arrowheads). Scale bar: 10μm. Entire hub area is encircled by white broken line. GSCs are attached to hub from surrounding area (not visible here).