Table 1.
Summary of H1-P1 induction of NF-κB activity in different cell lines of different cell types
Cells were treated with 100 nm H1-P1 for 4 h as analyzed by EMSA. +, a positive induction of NF-κB activity; −, no induction of NF-κB activity; +/−, a very weak induction of NF-κB activity. MM, multiple myeloma; MCL, mantle cell lymphoma; AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia.
| Cell line | Cell type | H1-P1 |
|---|---|---|
| RPMI8226 | MM | + |
| H929 | MM | + |
| MM.1S | MM | + |
| U266 | MM | + |
| Jeko-1 | MCL | + |
| z138 | MCL | + |
| Loucy | MCL | − |
| 721 | Lymphoblast | − |
| DHL4 | B cell lymphoma | + / − |
| KG-1 | Macrophages (AML) | − |
| RS4;11 | Bone marrow ALL | − |
| J45.01 | T-cell ALL | − |
| REH | ALL lymphocytes (non-B, non-T) | − |
| KIT225 | Lymphocytic leukemia T cells | + |
| U-937 | Histiocytic lymphoma (monocytes) | − |
| HEK293 | Human embryonic kidney | − |
| MEF | Mouse embryonic fibroblasts | − |