Table 1.

Surface plasmon resonance assessment of SPIN proteins binding to various forms of MPO

Analyte	Surface	KD	kon	Error kon	koff	Error koff	χ2
		nm	m−1s−1	m−1s−1	s−1	s−1
SPIN	Native MPO	9.3	5.37 × 105	3.5 × 103	4.99 × 10−3	3.0 × 10−5	0.148
SPIN	Human rMPO	11.8	4.46 × 105	1.5 × 103	5.24e × 10−3	1.5 × 10−5	0.128
SPIN(46–105)	Native MPO	29.8	6.19 × 105	2.3 × 103	1.85 × 10−2	3.0 × 10−5	0.102
SPIN(46–105)	Human rMPO	35.1	4.30 × 105	1.2 × 103	1.51 × 10−2	2.0 × 10−5	0.067
SPIN43–45→AAA	Native MPO	31.4	5.27 × 105	3.3 × 103	1.65 × 10−2	1.0 × 10−4	0.170
SPIN43–45→AAA	Human rMPO	32.6	4.88 × 105	1.2 × 103	1.59 × 10−2	1.8 × 10−5	0.043