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. Author manuscript; available in PMC: 2018 May 17.
Published in final edited form as: Chemistry. 2017 Apr 20;23(28):6724–6729. doi: 10.1002/chem.201605016

Figure 4.

Figure 4

(a) Long-term stability of β2AR solubilised in an RGA (RGA-C8, RGA-C9, RGA-C10, RGA-C11, RGA-C12 or RGA-C13) or DDM and (b) size-exclusion chromatography profiles of the receptor in selected detergents (RGA-C11, RGA-C13 and DDM). Protein stability was measured by the ligand-binding assay using the antagonist ([3H]-dihydroalprenolol (DHA)) during a two-day incubation at room temperature. For the size-exclusion chromatography analysis, detergent was exchanged from DDM to an RGA (RGA-C11 or RGA-C13) before applying each detergent-solubilised receptor for size-exclusion chromatography. Error bars, SEM, n = 3.