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. 2018 Feb 15;9:106. doi: 10.3389/fphys.2018.00106

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Copyright © 2018 Pathmanathan and Gray.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of process used to predict sudden cardiac death risk in Arevalo et al. (2016). A flowchart of the pipeline is shown in sub-figure (A). MR images are segmented [sub-figure (B)] to develop a patient-specific computational model which includes regions of scar tissue and border zone (“gray zone”) [sub-figure (C)]. A rule-based approach is used to specify fiber directions. The model is paced from 19 sites [sub-figure (D)] and with various pacing protocols and assessed for whether ventricular tachycardia is inducible. (Reproduced from Arevalo et al., 2016 with permission under Creative Commons license).