Table 2.

Results of breathing rate [1/min], breathing type [RU 0–4], lung auscultation [RU 0–4], interpleural pressure measurement [cmH2O], oxygen partial pressure (PO2) [mmHg], AaDO2 [mmHg], neutrophil percentage of TBS [%], nasal discharge [RU 0–3], endoscopic quantification of secretion (mucus) [RU 0–5] and viscosity [RU 0–5] depicted before (I), after 7 inhalations (II), and 6 weeks post‐treatment (III) with allergen & CpG treatment (n = 11 equine asthma‐affected horses) versus pure CpG treatment (n = 9 equine asthma‐affected horses) (RU = relative units, scoring system; mean ±SD)

	Breathing rate [1/min]			Breathing type [RU 0–4]			Auscultation [RU 0–4]			Interpleural pressure [cmH2O]
	I	II	III	I	II	III	I	II	III	I	II	III
Allergen+CpG (n = 11)	22.9 ± 7.1	21.1 ± 7.9	16.4 ± 8.0	2.5 ± 1.2	1.6 ± 1.7	1.1 ± 1.2	2.1 ± 1.3	1.7 ± 1.2	1.0 ± 0.7	28.5 ± 25.1	26.0 ± 24.2	22.8 ± 22.4
CpG (n = 9)	30.6 ± 10.2	25.3 ± 8.5	19.6 ± 11.3	2.9 ± 1.0	1.9 ± 1.6	1.6 ± 1.2	2.4 ± 1.1	1.7 ± 1.4	1.1 ± 1.0	23.8 ± 22.9	21.0 ± 21.8	16.9 ± 16.8

	AaDO2 [mmHg]			PO2 [mmHg]			Neutrophil percentage [%]
	I	II	III	I	II	III	I	II	III
Allergen+ CpG (n = 11)	23.1 ± 9.4	20.6 ± 15.3	13.0 ± 14.0	80.2 ± 11.8	85.3 ± 15.2	91.1 ± 15.6	68.2 ± 36.5	57.9 ± 34.3	51.8 ± 39.1
CpG (n = 9)	18.6 ± 9.0	18.6 ± 13.7	12.3 ± 12.2	86.3 ± 12.7	89.1 ± 13.1	95.4 ± 11.9	63.1 ± 34.6	63.8 ± 32.0	67.5 ± 39.0

	Nasal discharge [RU 0–3]			Quantification of secretion [RU 0–5]			Viscosity [RU 0–5]
	I	II	III	I	II	III	I	II	III
Allergen+ CpG (n = 11)	1.5 ± 0.5	0.6 ± 0.6	0.7 ± 0.5	3.0 ± 1.1	1.8 ± 1.3	1.6 ± 1.5	3.3 ± 0.7	2.0 ± 1.2	1.6 ± 1.5
CpG (n = 9)	1.3 ± 0.7	0.8 ± 0.7	0.8 ± 0.6	3.1 ± 1.1	2.3 ± 1.7	2.2 ± 1.4	3.0 ± 1.3	1.8 ± 1.5	2.2 ± 1.3