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. 2018 Feb 19;8:3252. doi: 10.1038/s41598-018-21663-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Mutational landscape of the ovarian fibrosarcoma. (A) Circos plot showing, at the outermost ring, the copy-number alterations found in the tumor. Mutations (SNV and InDels) in codifying genes are shown at the center. (B) Diagram of the DICER1 gene, showing its main domains. The mutation found in the tumor is marked at the upper side of the diagram, whereas the mutation found in the germinal DNA is depicted below it. (C) Diagram of the NF1 gene, showing its main domains. The mutation found in the tumor is shown.