Table 3.
Left ventricular diastolic function, assessed by echocardiography, of patients with multiple sclerosis and control subjects. Data are expressed as mean ± SD.
| Echo Parameters | Multiple Sclerosis | Control Subjects | P-value |
|---|---|---|---|
| E velocity (cm/s) | 74 ± 15 | 85 ± 16 | 0.002 |
| A velocity (cm/s) | 53 ± 11 | 60 ± 13 | 0.020 |
| E/A | 1.41 ± 0.30 | 1.45 ± 0.40 | NS |
| LA volume index (mm3/m2) | 24 ± 7 | 27 ± 8 | NS |
| FPV (cm/sec) | 47 ± 11 | 70 ± 21 | <0.001 |
| IVRT (sec) | 93 ± 11 | 69 ± 11 | <0.001 |
| E/FPV | 1.67 ± 0.40 | 1.32 ± 0.30 | 0.002 |
| E’(cm/s) | 9.3 ± 2.0 | 10.6 ± 2.0 | 0.010 |
| E’ online (cm/s) | 14 ± 4 | 16 ± 3 | 0.05 |
| E/E’ | 6.0 ± 1.4 | 6.0 ± 1.3 | NS |
| UTR (°/s) | −100 ± 36 | −129 ± 33 | 0.003 |
| LA SLS (%) | −12 ± 3 | −14 ± 2 | 0.027 |
E = early diastolic velocity; A = late diastolic velocity; LA = left atrial; FPV = flow propagation velocity; IVRT = isovolumetric relaxation time; E’ = 6-site averaged longitudinal myocardial offline diastolic velocity; E’ online = online longitudinal myocardial diastolic velocity; UTR = untwist rate, LA SLS = left atrial systolic longitudinal strain.