Figure 4.

Genetic and pharmacological dissection of the distinct excitability of type Ib, Is, and II synapses. Representative ΔF/F traces under 2- and 10-Hz stimulations (A, C), comparing WT control, WT with TEA (10 mM) and 4-AP (200 μM) treatments, Sh^M mutant and double mutant eag¹ Sh¹²⁰. Note the preferential effects of TEA on type II, and 4-AP, Sh^M and eag¹ Sh¹²⁰ on type Is synapses. B, D, Bar charts for sample statistics corresponding to the traces in A, C, with NMJ numbers and SEMs indicated. KW tests with Bonferroni correction were performed; *p < 0.05, **p < 0.01, ***p < 0.001.