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. 2017 Nov 24;29(2):489–499. doi: 10.1007/s00198-017-4310-y

Table 4.

Results related to therapeutic-failure definition

Question Wish (%) Prognosis (%)
A I D A I D
Therapeutic failure is to be considered when the BMD increment is not achieved in
a. 6 months 8.9 2.7 88.4 5.4 8.0 86.6
b. 1 year 35.7 4.5 59.8 33.9 8.9 57.1
c. 2 years 81.3 6.3 12.5 82.1 4.5 13.4
d. 3 years 77.7 8.0 14.3 75.9 9.8 14.3
e. 5 years 67.0 9.8 23.2 65.2 11.6 23.2
f. >5 years 51.8 13.4 34.8 48.2 19.6 32.1
Therapeutic failure is to be considered when a new fracture is diagnosed in the following:
a. 6 months 38.4 6.3 55.4 33.9 10.7 55.4
b. 1 year 77.7 8.0 14.3 77.7 8.0 14.3
c. 2 years 92.0 2.7 5.4 92.0 4.5 3.6
d. 3 years 90.2 4.5 5.4 88.4 7.1 4.5
e. 5 years 79.5 8.9 11.6 79.5 9.8 10.7
f. >5 years 69.6 11.6 18.8 68.8 13.4 17.9
Therapeutic failure is to be considered when a significant change in bone-remodeling markers is not achieved in the following:
a. 1 month 1.9 3.8 94.3 0.9 3.8 95.3
b. 3 months 73.6 4.7 21.7 59.4 6.6 34.0
c. 6 months 75.0 16.1 8.9 93.4 2.8 3.8
d. 1 year 90.6 4.7 4.7 89.6 5.7 4.7
e. 2 years 68.9 4.7 26.4 67.9 5.7 26.4
f. >2 years 65.1 2.8 32.1 61.3 4.7 34.0

Italic values represent the most answered option

A agreement, I indifference, D disagreement, wish (desire for it to happen), prognosis (belief that it will happen in a 5-year period)