Fig. 4.
The frequency of BaP-induced MN was evaluated in peripheral blood. a BaP dose-response data (± standard error) for micronuclei. Statistical results for the overall dose–response relationship are presented for both cell populations. The level of significance for the custom contrast results for each dose vs. control are indicated as follows: a = p < 0.0001; b = p < 0.001; c = p < 0.01; d = p < 0.05. RET reticulocyte; NCE normochromatic erythrocyte. b BMD100 values and two-sided 90% CIs (i.e., the range between the BMDL and BMDU) for % micronuclei for both cell populations. Where CIs overlap tissue responses cannot be considered different