Table 3.
Geometric mean titers of anti-measles, anti-mumps, and anti-rubella antibody concentrations* on day 0 and day 35 after vaccination in the per-protocol population.
| Vaccine component | Statistic | Day 0 |
Day 35 |
||
|---|---|---|---|---|---|
| DSJI (n = 161) | N-S (n = 157) | DSJI (n = 161) | N-S (n = 157) | ||
| Measles (IU/ml) | Geometric mean titer (GMT) | 0.19 | 0.17 | 5.48 | 5.94 |
| Two-sided 95% CI | (0.15, 0.26) | (0.13, 0.21) | (3.71, 8.11) | (3.92, 9.01) | |
| p-Value (between groupsα) | .4571 | .7813 | |||
| p-Value (within groupβ) | <.0001 | <.0001 | |||
| Mumps (ISR) | GMT | 0.29 | 0.29 | 3.83 | 3.66 |
| Two-sided 95% CI | (0.25, 0.32) | (0.25, 0.33) | (3.53, 4.14) | (3.39, 3.95) | |
| p-Value (between groupsα) | .9821 | .4293 | |||
| p-Value (within groupβ) | <.0001 | <.0001 | |||
| Rubella (IU/ml) | GMT | 3.25 | 3.04 | 95.27 | 107.06 |
| Two-sided 95% CI | (2.73, 3.86) | (2.77, 3.34) | (70.39, 128.95) | (79.02, 145.06) | |
| p-Value (between groupsα) | .5150 | .5914 | |||
| p-Value (within groupβ) | <.0001 | <.0001 | |||
*
IgG antibody titers were determined by ELISA (Trinity Biotech) for each vaccine component.
α
For comparing GMTs between the two study groups, the two-sample t-test was used.
β
For comparing GMTs within each group between day 0 and day 35, the paired t-test was used. The p-value is shown in the day 35 columns.