Table 3. Secondary End Points by Treatment Group.
| End Point | No./Total No. (%) | Unadjusted Risk Difference (95% CI), % | Adjusted Odds Ratio (95% CI)a | P Value | |
|---|---|---|---|---|---|
| Conventional Laparoscopic Surgery | Robotic-Assisted Laparoscopic Surgery | ||||
| CRM+b | 14/224 (6.3) | 12/235 (5.1) | 1.2 (−3.1 to 5.4) | 0.78 (0.35 to 1.76) | .56 |
| Mesorectal area = mesorectal plane | 173/223 (77.6) | 178/233 (76.4) | 1.2 (−6.5 to 8.9) | 0.94 (0.56 to 1.57) | .14 |
| Intraoperative complication | 34/230 (14.8) | 36/236 (15.3) | −0.5 (−6.0 to 7.0) | 1.02 (0.60 to 1.74) | .94 |
| Postoperative complication within 30 d of operation | 73/230 (31.7) | 78/236 (33.1) | −1.3 (−9.8 to 7.2) | 1.04 (0.69 to 1.58) | .84 |
| Postoperative complication >30 d and ≤6 mo after operation | 38/230 (16.5) | 34/236 (14.4) | 2.1 (−4.5 to 8.7) | 0.72 (0.41 to 1.26) | .25 |
| Mortality within 30 d of operationc | 2/230 (0.9) | 2/236 (0.8) | 0.02 (−1.7 to 1.7) | NA | NA |
Abbreviations: CRM+, circumferential resection margin positivity; NA, not applicable.
a
Adjusted for sex, body mass index class, preoperative radiotherapy, intended procedure, and operating surgeon.
b
Defined as tumor cells within 1 mm of the circumferential resection margin on histological analysis.
c
Adjusted analysis was not performed for mortality within 30 days of operation due to the small number of events.