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. 2018 Feb 14;11:13–22. doi: 10.2147/SCCAA.S151763

Table 1.

In vitro development of ZFREs reconstructed with BM-MSC or fibroblasts as nuclear donors

Groups ZFREs No. of embryos (wells)* No. of cleaved embryos (%) Blastocyst production
No. % per embryo % per ZFRE
AF 4527 1509 3875 (85.6)a 492 32.6a 10.9a
MSC 3432 1144 3095 (90.2)b 622 54.4b 18.1b

Notes:

a,b

Values with different superscripts in a column are significantly different (Fisher’s exact test p<0.05).

*

Embryo aggregation was performed and each well contained three ZFREs.

Abbreviations: ZFREs, zona-free reconstructed embryos; BM-MSCs, bone marrow–derived mesenchymal stem cells; AF, adult fibroblasts; MSC, mesenchymal stem cell.