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. Author manuscript; available in PMC: 2018 Feb 20.
Published in final edited form as: Org Lett. 2017 Aug 4;19(16):4263–4266. doi: 10.1021/acs.orglett.7b01911

Scheme 2.

Scheme 2

Macrocyclization of Peptides Containing Two Unprotected Cysteinesa

aYield determined by LC-MS analysis. bRequired 15% acetonitrile solution to fully dissolve bis-palladium reagents.