Table 1.
Demographic Characteristics
| Characteristic | TEAM (n=69) | Mayo, All Cases (n=732) | Mayo, Early-Onset Cases (n=192) | Mayo, Late-Onset Cases (n=256) | Controls (n=776) |
|---|---|---|---|---|---|
| Age at enrollment, mean (SD), y | 10.5 (2.9) | 42.0 (15.1) | 35.9 (12.8) | 47.3 (15.2) | 52.5 (21.9) |
| Body mass index at enrollment, mean (SD), kg/m2 | 19.4 (4.2) | 30.1 (7.0) | 30.2 (7.3) | 29.6 (6.7) | 26.0 (8.5) |
| Sex, male, No. (%) | 30 (43.5) | 303 (41.4) | 65 (33.9) | 122 (47.7) | 318 (41.0) |
| Race, Caucasian, No. (%) | 69 (100) | 732 (100) | 192 (100) | 256 (100) | 776 (100) |
| Age of onset, mean (SD) | 4.9 (2.5) | 24.8 (13.9) | 13.7 (3.7) | 33.2 (12.8) | ... |
| Attention-deficit/hyperactivity disorder, No. (%) | 67 (97.1) | 183/691 (26.5) | 55/184 (29.9) | 54/244 (22.1) | ... |
| Psychosis, No. (%) | 57 (82.6) | 323/716 (45.1) | 109/187 (58.3) | 140/254 (55.1) | ... |
| Mixed episodes, No. (%) | 66 (95.7) | 92/575 (16.0) | 27/186 (14.5) | 38/244 (15.6) | ... |
| Separation anxiety disorder, No. (%) | 25 (36.2) | ... | ... | ... | ... |
| Panic disorder, No. (%) | 0 (0) | 224/700 (32.0) | 74/185 (40.0) | 66/249 (26.5) | ... |
| Obsessive-compulsive disorder, No. (%) | 14 (20.3) | 109/703 (15.5) | 38/184 (20.7) | 34/246 (13.8) | ... |
| Social phobia, No. (%) | 20 (29.0) | ... | ... | ... | ... |
| Social anxiety disorder, No. (%) | … | 179/696 (25.7) | 50/182 (27.5) | 68/247 (27.5) | ... |
| Generalized anxiety disorder, No. (%) | 23 (33.3) | 353/706 (50.0) | 87/183 (47.5) | 124/249 (49.8) | ... |
| Any substance dependence or abuse, No. (%) | 1 (1.4) | 411/722 (56.9) | 112/189 (59.3) | 138/255 (54.1) | ... |
Abbreviation: TEAM, Treatment of Early Age Mania study.