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. 2018 Feb 20;19:61. doi: 10.1186/s12891-018-1966-1

Table 3.

Genotypic and allelic distribution of four SNP loci in the exon regions of BMPR-IA gene between OPLL patients and non-OPLL Controls

SNPs -349C > T 4A > C 1327C > T 1395G > C
exon1 exon3, Pro2Thr exon11, Arg443Cys exon12, Pro465Pro
Genotype CC CT TT AA AC CC CC CT TT GG GC CC
OPLL (n = 356) 83 190 83 145 143 68 206 85 65 120 156 80
Control (n = 617) 297 246 74 283 284 50 370 148 99 240 222 155
Pearson Chi-Square Test P < 0.001 P < 0.001 P = 0.662 P = 0.436
Allele C T A C C T G C
OPLL 356 356 433 279 497 215 396 316
Control 840 394 850 384 888 346 702 532
Pearson Chi-Square Test P < 0.001 P < 0.001 P = 0.311 P = 0.586