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. 2018 Feb 20;13:34. doi: 10.1186/s13023-018-0775-9

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© The Author(s). 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Change in FEV₁ before and after sirolimus in paired groups. Zero on the horizontal axis indicates the day on which sirolimus therapy was initiated; negative and positive numbers indicate years before and after the initiation of sirolimus administration, respectively. Abbreviations: FEV₁, forced expiratory volume in 1 s