Table 2.

Characterization and location of PrPSc deposits in tg66 mice injected with Y226X human brain tissue

	Brain regionsa
Dpib	Pons	Thalamus	Superior Colliculus	Hypothalamus	Cerebral cortex
593	P	C	C	P	neg
601	P&PN	C	C	PN	PN
716	P&PN	neg	neg	P	P (rare)
718	P&PN	neg	C (rare)	neg	C (weak)

^a-Types of PrPSc deposits seen in the indicated brain regions: P = plaque-like, PN = perineuronal linear or pericellular deposits, C = coarse deposits in neuropil, neg = negative

^b-Days post-injection with human Y226X brain tissue