Table 1.
Baseline characteristics of patients with Alzheimer’s disease according to outcome
| No. of patients | Alive (n = 403) | Died (n = 213) | p Value | |
|---|---|---|---|---|
| Demographics | ||||
| Female sex, n (%) | 616 | 218 (54) | 91 (43) | 0.007 |
| Age, years | 616 | 66 ± 7 | 69 ± 9 | 0.000 |
| APOE ε4 carrier, n (%) | 562 | 250 (67) | 119 (63) | 0.280 |
| Years of education | 616 | 11 ± 3 | 11 ± 3 | 0.675 |
| Years of complaints | 611 | 3.2 ± 2.6 | 2.8 ± 2.0 | 0.066 |
| Years to outcome | 616 | 5.3 ± 1.8 | 4.3 ± 2.1 | 0.000 |
| Activities of daily living (DAD) | 372 | 83 ± 17 | 82 ± 17 | 0.450 |
| Medical history | ||||
| Smoking, n (%) | 599 | 185 (47) | 98 (49) | 0.640 |
| Hypertension, n (%) | 616 | 127 (32) | 77 (36) | 0.245 |
| Hypercholesterolemia, n (%) | 616 | 103 (26) | 46 (22) | 0.275 |
| Diabetes mellitus, n (%) | 616 | 31 (8) | 15 (7) | 0.770 |
| Cardiovascular disease, n (%) | 616 | 71 (18) | 53 (25) | 0.032 |
| No. of medications | 616 | 2.0 ± 2.0 | 2.4 ± 2.1 | 0.062 |
Abbreviations: APOE Apolipoprotein E, DAD Disability Assessment for Dementia (range 0–100)
Years to outcome: in case of alive, follow-up duration; in case of died, duration to death
Data are presented as mean ± SD unless otherwise specified. Group differences were calculated using Student’s t test for continuous variables. For categorical variables, the chi-square test was used