Table 2.
Prevalence of msp-1 K1, MAD20, and RO33 allelic variants collected from Plasmodium falciparum isolates along Grande Comore Island in 2006–2007 and 2013–2016 periods
| K1 allele | Number of isolates (%)a | MAD20 allele | Number of isolates (%)a | RO33 allele | Number of isolates (%)a | |||
|---|---|---|---|---|---|---|---|---|
| 2006–2007 | 2013–2016 | 2006–2007 | 2013–2016 | 2006–2007 | 2013–2016 | |||
| (n = 40) | (n = 44) | (n = 20) | (n = 12) | (n = 42) | (n = 54) | |||
| K1-1 | 2 (5.0) | 0 (0)* | MAD20-1 | 5 (25.0) | 5 (41.6)** | RO33-1 | 7 (21.2) | 32 (59.3)** |
| K1-2 | 0 (0) | 2 (4.5)* | MAD20-2 | 1 (5.0) | 2 (16.6)** | RO33-2 | 2 (6.1) | 3 (5.6) |
| K1-3 | 1 (2.5) | 0 (0) | MAD20-3 | 2 (10.0) | 5 (41.6)** | RO33-3 | 8 (24.2) | 1 (1.9)** |
| K1-4 | 3 (7.5) | 0 (0)** | MAD20-4 | 3 (15.0) | 0 (0)** | RO33-4 | 2 (6.1) | 1 (1.9) |
| K1-5 | 0 (0) | 5 (11.4)** | MAD20-5 | 2 (10.0) | 0 (0)** | RO33-5 | 4 (12.1) | 1 (1.9)** |
| K1-6 | 3 (7.5) | 2 (4.5) | MAD20-6 | 2 (10.0) | 0 (0)** | RO33-6 | 2 (6.1) | 0 (0)** |
| K1-7 | 5 (12.5) | 5 (11.5) | MAD20-7 | 1 (5.0) | 0 (0)* | RO33-7 | 0 (0) | 3 (5.6)* |
| K1-8 | 0 (0) | 3 (6.8)** | MAD20-8 | 1 (5.0) | 0 (0)* | RO33-8 | 3 (9.1) | 0 (0)** |
| K1-9 | 2 (5.0) | 2 (4.5) | MAD20-9 | 3 (15.0) | 0 (0)** | RO33-9 | 0 (0) | 2 (3.7) |
| K1-10 | 3 (7.5) | 0 (0)** | RO33-10 | 3 (9.1) | 0 (0)** | |||
| K1-11 | 2 (5.0) | 8 (18.2)** | RO33-11 | 0 (0) | 8 (14.8)** | |||
| K1-12 | 2 (5.0) | 2 (4.5) | RO33-12 | 2 (6.1) | 3 (5.6) | |||
| K1-13 | 3 (7.5) | 9 (20.5)** | ||||||
| K1-14 | 0 (0) | 2 (4.5)* | ||||||
| K1-15 | 2 (5.0) | 0 (0)* | ||||||
| K1-16 | 1 (2.5) | 0 (0) | ||||||
| K1-17 | 3 (7.5) | 0 (0)** | ||||||
| K1-18 | 8 (20.0) | 4 (9.1)* | ||||||
aStatistically significant differences for comparison with isolates circulating in 2006–2007 from Grande Comore island (* P < 0.05; ** P < 0.01) using Mann–Whitney U test