Table 3.
Prevalence of msp-2 FC27 and 3D7 allelic variants collected from Plasmodium falciparum isolates along Grande Comore Island in 2006–2007 and 2013–2016 periods
| FC27 allele | Number of isolates (%)a | 3D7 allele | Number of isolates (%)a | ||
|---|---|---|---|---|---|
| 2006–2007 (n = 62) | 2013–2016 (n = 80) | 2006–2007 (n = 56) | 2013–2016 (n = 33) | ||
| FC27-1 | 4 (6.4) | 8 (10.0) | 3D7-1 | 4 (7.1) | 2 (6.1) |
| FC27-2 | 1 (1.6) | 3 (3.8) | 3D7-2 | 19 (34.0) | 2 (6.1)** |
| FC27-3 | 2 (3.2) | 2 (2.5) | 3D7-3 | 3 (5.4) | 3 (9.1) |
| FC27-4 | 0 (0) | 3 (3.7) | 3D7-4 | 4 (7.2) | 0 (0)** |
| FC27-5 | 8 (12.9) | 0 (0)** | 3D7-5 | 3 (5.4) | 0 (0)* |
| FC27-6 | 3 (4.8) | 0 (0)** | 3D7-6 | 1 (1.8) | 0 (0) |
| FC27-7 | 6 (9.7) | 0 (0)** | 3D7-7 | 0 (0) | 3 (9.1)** |
| FC27-8 | 0 (0) | 2 (2.5) | 3D7-8 | 3 (5.4) | 2 (6.1) |
| FC27-9 | 2 (3.2) | 3 (3.8) | 3D7-9 | 6 (10.7) | 16 (48.5)** |
| FC27-10 | 8 (12.9) | 2 (2.5)** | 3D7-10 | 2 (3.6) | 0 (0) |
| FC27-11 | 4 (6.5) | 0 (0)** | 3D7-11 | 3 (5.4) | 2 (6.1) |
| FC27-12 | 3 (4.8) | 2 (2.5) | 3D7-12 | 0 (0) | 3 (9.1)** |
| FC27-13 | 3 (4.8) | 3 (3.8) | 3D7-13 | 4 (7.1) | 0 (0)** |
| FC27-14 | 7 (11.3) | 47 (58.8)** | 3D7-14 | 1 (1.8) | 0 (0) |
| FC27-15 | 0 (0) | 2 (2.5) | 3D7-15 | 3 (5.4) | 0 (0)* |
| FC27-16 | 5 (8.1) | 0 (0)** | |||
| FC27-17 | 0 (0) | 1 (1.3) | |||
| FC27-18 | 0 (0) | 2 (2.5) | |||
| FC27-19 | 3 (4.8) | 0 (0)** | |||
| FC27-20 | 1 (1.6) | 0 (0) | |||
| FC27-21 | 2 (3.2) | 0 (0) | |||
a Statistically significant differences for comparison with isolates circulating in 2006–2007 from Grande Comore island (* P < 0.05; ** P < 0.01) using Mann–Whitney U test