Table 2.
FTO genotype and measures of body weight stratified by ethnicity
| rs1558902 genotype | ||||
|---|---|---|---|---|
| TT | TA | AA | p | |
| Caucasians | ||||
| Subjects (n) | 256 | 367 | 136 | |
| BMI (kg/m2) | 22.9 ± 0.2a | 23.6 ± 0.2 | 23.4 ± 0.3 | 0.07 |
| Waist circumference (cm) | 74.7 ± 0.5a | 76.4 ± 0.5b | 75.6 ± 0.8ab | 0.03 |
| East Asians | ||||
| Subjects (n) | 422 | 125 | 11 | |
| BMI (kg/m2) | 21.7 ± 0.1b | 22.0 ± 0.2b | 24.5 ± 1.2a | 0.004 |
| Waist circumference (cm) | 71.0 ± 0.4b | 71.4 ± 0.6b | 77.0 ± 3.0a | 0.03 |
| South Asians | ||||
| Subjects (n) | 84 | 77 | 13 | |
| BMI (kg/m2) | 23.7 ± 0.4 | 23.6 ± 0.5 | 24.8 ± 1.8 | 0.93 |
| Waist circumference (cm) | 76.4 ± 1.1 | 75.2 ± 1.5 | 77.2 ± 3.8 | 0.96 |
Differences between groups assessed using GLMs adjusted for age, sex, and energy intake
Groups without a common letter differ after a Tukey-Kramer post hoc test (p<0.05)
aMean ± SE (all such values)