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. 2018 Feb 13;24:891–896. doi: 10.12659/MSM.906098

Table 2.

Effect of corilagin on passive cutaneous anaphylaxis, active anaphylaxis and degranulation of mast cell.

Sr. No. Group Passive cutaneous anaphylaxis Active anaphylaxis Mast cell degranulation
Blueing reaction mm3 Behavioural symptoms (% of mortality) Respiratory score Intact Degranulated
1 Control 00 Normal 00 (00) 100 00
2 Negative control 78.39±3.15 Respiratory distress/collapse 3–5 min (70%) 8.80±5.2 (65%) 22.62±2.94## 79.32±4.72##
3 Corilagin 10 mg/kg 69.17±3.09 Dysponea 5–8 min (40%) 6.25±3.15 (40%) 31.72±2.45* 67.37±4.31**
4 Corilagin 20 mg/kg 54.92±2.90 Dysponea 15–20 min (25%) 4.10±1.28 (25%) 43.89±3.56** 56.18±3.78**
5 Corilagin 40 mg/kg 47.36±1.97 Normal 2.74±1.45 (15%) 55.73±4.71** 44.27±3.26**
6 STD Dexomethasone 43.18±2.69 Normal 2.36±0.75 (15%)
Ketotifen 62.39±4.26** 38.29±2.46**

Means ±SD (n=6),

##

p<0.01 than control,

*

p<0.05,

**

p<0.01 than negative control.