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. Author manuscript; available in PMC: 2018 Feb 20.
Published in final edited form as: Eur J Neurosci. 2016 May 11;43(12):1661–1673. doi: 10.1111/ejn.13248

Fig. 3.

Fig. 3

TTX abolishes the AMPH-induced activation of dopamine transients. AMPH-induced dopamine elevations following intra-VTA infusions of aCSF (A) and TTX (B) in representative recordings. Black triangle indicates time point when individual background-subtracted cyclic voltammograms were derived (insets). (C) Transient frequency (top), amplitude (middle) and duration (bottom) at baseline (Pre), following intra-cranial (i.c.) infusions, intravenous saline (Sal), and intravenous AMPH. All measures were abolished by TTX. Data are expressed as mean + SEM. *P < 0.001 vs. Pre (within-group comparison); ^P < 0.001 vs. aCSF (between-group comparison).