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. Author manuscript; available in PMC: 2018 Feb 20.
Published in final edited form as: Shock. 2009 Dec;32(6):614–620. doi: 10.1097/SHK.0b013e3181a4fd8f

Fig. 3. Rimonabant (RMN) administration prevents the rise in extracellular NE concentrations induced by LPS in conscious rats.

Fig. 3

Groups of six rats were treated with intracerebroventricular rimonabant (250 ng) or saline, followed 2 min later by intravenous LPS (1 mg/kg) or saline. Extracellular fluid NE concentrations were sampled at 10-min intervals by microdialysis and analyzed by HPLC. Statistical analysis was performed using two-way repeated-measure ANOVA, followed by Tukey test. *P < 0.05, significantly different from basal concentrations of NE before LPS injection. †P < 0.05, significantly different from the LPS group.