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. Author manuscript; available in PMC: 2018 Dec 18.
Published in final edited form as: Analyst. 2017 Dec 18;143(1):21–32. doi: 10.1039/c7an01046j

Figure 4.

Figure 4

Schematic of the CMACS device. Laminar flow architecture keeps the sample stream near the channel walls and flows to waste. Angled magnetized Ni strips guide the magnetic beads containing bound oligos into the central buffer stream which is collected through a separate outlet. Optical micrographs show the device during operation at A) the channel wall, B) the buffer stream, and C) the outlet. The large distance m prevents diffusion of unwanted sequences into the central stream. Adapted from Lou et al73 Copyright 2009 National Academy of Sciences.