Table 2.
Genes | SCs | Mast cells | Endothelial cell |
AHR pathway | |||
AHR | 426 | 11 | 6 |
AHRR | 200 | 1,342 | 78 |
ARNT | 1,105 | 492 | 479 |
Trp metabolism | |||
IDO1 | 10 | NE | 2 |
IDO2 | NE | NE | NE |
TDO2 | 14 | 3 | NE |
Myelin markers | |||
S100B | 66,360 | 2 | 6 |
MPZ | 24,336 | 4 | 5 |
AHR is predominantly expressed in SCs compared with mast cells and endothelial cells. Total RNA was isolated from normal human tissues. The gene mRNA levels (calculated as described in Materials and Methods) were based on the amount of the target message relative to the endogenous control TBP message, to normalize the starting amount and quality of total RNA. NE, not expressed.