Table 2.

Factors associated with survival in ATTRwt (n = 101)

Variable	Univariate analysis Hazard Ratio (95% CI)	P	Multivariate analysis Hazard Ratio (95% CI)	P
TTR (mg/dL)	0.93 (0.88 – 0.98)	0.007	0.89 (0.84 – 0.95)	< 0.001
cTn-I (ng/mL)	5.12 (2.43 – 10.81)	< 0.001	8.06 (3.01 – 21.57)	< 0.001
BNP (pg/mL)	1.001 (1.001 – 1.002)	0.002
LVEF (%)	0.96 (0.94 – 0.99)	0.001	0.97 (0.94 – 0.99)	0.01
Creatinine (mg/dL)	2.02 (1.14 – 3.60)	0.02
Uric acid (mg/dL)	1.14 (1.02 – 1.28)	0.02
Sedimentation rate (mm/hr)	1.03 (1.01 – 1.04)	0.001

ATTRwt indicates wild-type transthyretin amyloidosis; TTR, transthyretin; cTn-I, cardiac troponin I; BNP, B-type natriuretic peptide; LVEF, left ventricular ejection fraction; and CI, confidence interval