Table 4.
Association between hippocampus dose and neurocognitive test deterioration
| Mean dose (EQD2/2) | ||||||
|---|---|---|---|---|---|---|
| Bilateral hippocampi | P value | Right hippocampus | P value | Left hippocampus | P value | |
| SVLT-Total recall | 0.033a | 0.398 | 0.013a | |||
| No Deterioration (n = 23) | 10.6 ± 6.5 | 15.7 ± 16.8 | 11.8 ± 14.1 | |||
| Deterioration (n = 3) | 20.3 ± 11.5 | 7.2 ± 1.7 | 37.7 ± 27.6 | |||
| SVLT-Delayed recall | 0.115 | 0.558 | 0.074 | |||
| No Deterioration (n = 24) | 11.0 ± 6.7 | 15.2 ± 16.6 | 13.1 ± 15.0 | |||
| Deterioration (n = 2) | 19.8 ± 16.3 | 8.2 ± 0.1 | 36.0 ± 38.9 | |||
| SVLT-Recognition | 0.003a | 0.427 | 0.001a | |||
| No Deterioration (n = 23) | 10.2 ± 6.0 | 13.8 ± 15.8 | 11.1 ± 11.7 | |||
| Deterioration (n = 3) | 23.3 ± 9.4 | 21.8 ± 19.5 | 43.1 ± 30.9 | |||
| RCFT-COPY | 0.469 | 0.211 | 0.261 | |||
| No Deterioration (n = 20) | 11.1 ± 6.6 | 16.9 ± 17.7 | 12.7 ± 14.9 | |||
| Deterioration (n = 6) | 13.7 ± 10.7 | 7.5 ± 3.7 | 22.0 ± 24.6 | |||
| RCFT-Immediate recall | 0.156 | 0.513 | 0.081 | |||
| No Deterioration (n = 24) | 11.1 ± 6.6 | 15.3 ± 16.5 | 13.1 ± 15.0 | |||
| Deterioration (n = 2) | 19.0 ± 17.4 | 7.4 ± 1.2 | 36.0 ± 39.4 | |||
| RCFT-Delayed recall | 0.156 | 0.513 | 0.081 | |||
| No Deterioration (n = 24) | 11.1 ± 6.6 | 15.3 ± 16.5 | 13.1 ± 15.0 | |||
| Deterioration (n = 2) | 19.0 ± 17.4 | 7.4 ± 1.2 | 35.6 ± 39.4 | |||
| RCFT-Recognition | 0.042a | 0.406 | 0.257 | |||
| No Deterioration (n = 23) | 10.6 ± 6.5 | 13.8 ± 16.0 | 13.4 ± 15.2 | |||
| Deterioration (n = 3) | 19.9 ± 11.5 | 22.1 ± 20.9 | 25.8 ± 32.7 | |||
Numbers are represented as mean ± SD
SVLT Seoul Verbal Learning Test, RCFT Rey Complex Figure Test and Recognition Trial
aindicate statistical significance by student’s t-test