TABLE 5.
Grade of TR and mortality for subgroup: Cox proportional hazard regression model multivariable analysis
| Variable | Category | HR | CI (95%) | P value |
|---|---|---|---|---|
| Grade of TR (n=11,336) | ||||
| None (%) | Ref | - | ||
| Mild (%) | 1.11 | 1.0–1.25 | .060 | |
| Moderate (%) | 1.37 | 1.14–1.63 | <.0001 | |
| Severe (%) | 2.29 | 1.61–3.26 | <.0001 | |
| Male gender | 0.89 | 0.8–.98 | .019 | |
| BMI | 0.99 | .98–1.0 | .008 | |
| Race | ||||
| Caucasian | Ref | - | ||
| Asian | 0.66 | 0.36–1.23 | .191 | |
| Black | 0.83 | 0.58–1.17 | .287 | |
| Hispanic | 0.67 | 0.45–1.0 | .051 | |
| Others | 0.8 | 0.48 to 1.32 | .381 | |
| Past smoker | 1.31 | 1.18–1.45 | <.0001 | |
| Current smoker | 1.11 | 0.92–1.33 | .263 | |
| Diabetes | 1.51 | 1.35–1.68 | <.0001 | |
| HLD | 0.91 | 0.81–1.02 | .105 | |
| HTN | 1.34 | 1.18–1.51 | <.0001 | |
| PVD | 1.46 | 1.3–1.64 | <.0001 | |
| Creatinine | 1.48 | 1.4–1.56 | <.0001 | |
| Status | ||||
| Elective (%) | Ref | - | ||
| Urgent (%) | 1.35 | 1.21–1.49 | <.0001 | |
| Emergent (%) | 1.36 | 0.99–1.87 | .057 | |
Model stratified by operation year, age, left and right ventricular function, and type of surgery. 2,636 death events during the follow-up. C-statistic = 0.64; HR, hazard ratio; CI, confidence interval; TR, tricuspid regurgitation; BMI, body mass index; HLD, hyperlipidemia; HTN, hypertension; PVD, peripheral vascular disease.