Figure 4.

Analysis of gene expression changes which result from PLZF knockdown reveals gene sets and cellular processes that are important for HESC decidualization. (A) DAVID analysis and GSEA of genes for which transcript levels significantly altered with PLZF knockdown (at day 3 EPC treatment). (B) As an example, quantitative real-time PCR analysis confirms that normal transcriptional induction of cytokine and interleukin gene family members is significantly attenuated with PLZF depletion; *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001.