Table 1.

Function of Wnt ligands in early neurodevelopment processes.

Ligand	Neurodevelopment Process
Wnt1	AP (Hollyday et al., 1995), FB (Molven et al., 1991; Hollyday et al., 1995; Lagutin et al., 2003), MHB (Wolda et al., 1993; Hollyday et al., 1995; Lagutin et al., 2003; Buckles et al., 2004), HB (Riley et al., 2004), SC (Parr et al., 1993)
Wnt2b	MHB (Kunz et al., 2004)
Wnt3	AP, SC (Roelink and Nusse, 1991), FB (Braun et al., 2003)
Wnt3a	AP, FB (Hollyday et al., 1995), MHB (McMahon et al., 1992; Buckles et al., 2004), HB (Riley et al., 2004), SC (Parr et al., 1993)
Wnt4	AP, FB, MHB (Hollyday et al., 1995), HB (McGrew et al., 1992)
Wnt5a	FB (Hollyday et al., 1995)
Wnt7b	FB (Hollyday et al., 1995)
Wnt8a	NE (Baker et al., 1999), HB (Hume and Dodd, 1993)
Wnt8b	FB (Hollyday et al., 1995; Houart et al., 2002), MHB (Kunz et al., 2004), HB (Riley et al., 2004)
Wnt10a	FB, HB (Kelly et al., 1993)
Wnt10b	MHB (Buckles et al., 2004), HB (Riley et al., 2004)

Abbreviations: NE : Neural Specification of Ectoderm; AP : Anterior-Posterior Patterning of the Neural Tube; FB : Patterning of the Forebrain; MHB : Induction of the Midbrain-Hindbrain Boundary; HB : Specification and Segmentation of the Hindbrain; SC : Induction and Patterning of the Spinal Cord.