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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: NMR Biomed. 2018 Jan 12;31(3):10.1002/nbm.3887. doi: 10.1002/nbm.3887

Figure 4. Comparison of caudal to rostral change in voxel intensity in the current study versus caudal to rostral change in dendritic branching from our previous study.

Figure 4

A) Percent change in ROI mean voxel intensities of Mn2+ 24 hours after injection of 66 mg/kg MnCl2, using T1 weighted MRI scanning. The x-axis represents caudal to rostral axis of the ventrolateral medulla relative to the caudal pole of the facial nucleus (designated as FN0 and 0 μm). A pattern of increasing Mn2+ uptake was seen from the caudal to rostral levels of the RVLM (*, p<0.05, main effect). B) Pattern of increased dendritic branching from caudal to rostral areas of the ventrolateral medulla observed in bulbospinal catecholaminergic RVLM neurons from our previous study (*, p<0.05, compared to 600 μm; modified from Mischel et al., 2014). Grey boxes represent the functionally and anatomically defined region of the RVLM.