Table 2.
Time course of absolute voxel intensities in the pituitary of rats injected with 33 or 66 mg/kg MnCl2.
| Absolute Voxel Intensity in the Pituitary Gland | ||
|---|---|---|
| Time point | 33 mg/kg MnCl2 (n=5) | 66 mg/kg MnCl2 (n=5)# |
| Baseline Scan | 1479 ± 29 | 1457 ± 34 |
| 1 day Scan | 2689 ± 31* (Δ 67±12%) | 2758 ± 43* (Δ 90±4%) |
| 8 day Scan | 2091 ± 109* (Δ 33± 8%) | 2279 ± 76* (Δ 57±7%) |
| 15 day Scan | 1816 ± 39* (Δ 20± 3%) | 2008 ± 39* (Δ 38±4%) |
| 22 day Scan | 1699 ± 26* (Δ 13± 3%) | 1823 ± 23* (Δ 21±4%) |
Absolute voxel intensities expressed in arbitrary units and percent change expressed relative to the Baseline Scan in each animals for each dose.
*
p<0.05 main effect of time compared to baseline;
#
p<0.05 main effect of dose.