Table 1.

Peripheral insulin resistance in 9-month-old Tg2576 and 16-month-old 3xTg-AD mice compared to age matched WT mice.

Glucose Tolerance Test
Tg2576 vs. WT (Rodriguez-Rivera et al., 2011)
Age	Fasting	15min	30min	45min	60min	90min	120min	210min
5 Months	ns	ns	ns	ns	ns	ns	ns	ns
9 Months	ns	↑, **	↑, ***	↑, **	↑, **	↑, *	ns	ns
3xTg-AD vs. WT (Fig. 1)
Age	Fasting	15min	30min	45min	60min	90min	120min	210min
10 Months	ns	ns	↓, *	ns	ns	ns	ns	ns
16 Months	↑, ***	↑, *	ns	↑, *	↑, **	↑, **	↑, *	ns

Arrows indicate a significant increase (↑) or decrease (↓) in glucose level over age-matched WT.

Abbreviations: ns = non-significant, GTT = Glucose tolerance test.

^*p < 0.05,

^**p < 0.01,

^***p < 0.001.