Table IV.
Validated target genes of 8 differentially expressed miRNAsa.
| miRNA | Regulation | Target genes |
|---|---|---|
| mmu-miR-28b | Down | Slc7a2, Nr3c1, Timm17b, Timm17b, 2010109I03Rik, Tars2, Sl×1b, Tns4, Prss43, Pld5, Ccdc78, Tmppe |
| mmu-miR-296-3p | Down | Ctla2a, Gna14, Igf1r, Dusp8, Tfam, Tnf, Cxcl11, Car5b, Nsa2, Clvs1, Phf14, Phf14, Braf, Mcmdc2, Prss43 |
| mmu-miR-669a-3p | Up | Cry2, Cd47, Kras, Shh, Zfp37, Rnf11, Ccdc82, 2610002M06Rik, Wdfy3, 1700019G17Rik, Fam159b, Cml2, Arrdc3, Sipa1l1, Csde1, Gm4944, Gm7616 |
| mmu-miR-691 | Up | Cbln2, Cdk7, Inpp5d, Ndrg1, Sp4, Pcgf2, Scd3, Arl6ip1, Wtap, Atp2b1, 1700025G04Rik, Sik3, Dapl1, Adamtsl1, Utp23, Cnnm1, Hlcs |
| mmu-miR-223-3p | Up | Abca1, Slc33a1, Macf1, Ank3, Prdx6, Aplp2, Atp9a, Atrn, Pcdh15, Casp9, Cbx5, Cckbr, Cdkn1b, Celf1, Dag1, Ddn, Enc1, Eps15, Ercc3, F2r, F3, Fmn1, Srgap2, Fut9, Gabra6, Gabrg1, Gria2, Grin2b, Trip12, Gzmb, Sdc2, Igf1r, Itgb1, F11r, Kcnj10, Kcnj3, Kif1b, Klf12, Kpna1, Kras, Ktn1, Ldlr, Zbtb7a, Smad5, Mecp2, Mef2c, Mt2, Map1b, Myo1c, Napb, Nf1, Nfib, Ntrk2, Dusp8, Pdgfra, Enpp1, Pdpk1, Pea15a, Peg3, Pgr, Phka1, Pik3r3, Prkcb, Pkia, Plod1, Plxna2, Prkar2b, Prnp, Ptpru, Pvt1, Rest, Rgs2, Xpr1, Rtn3, Scd1, Scn8a, Sdpr, Sept8, Serf1, Sox6, Stat3, Syn1, Syp, Syt4, Tnfaip1, Utrn, Vim, Xpc, Ywhaz, Zfp26, Akt3, Apc2, Ets1, Gm16515, Gnpda1, Mapk10, B3galt1, B3galnt1, Syn3, Trp53bp1, Amot, Nrep, Ubfd1, Mga, Rnf11, Fbxw7, Tmod2, Mfhas1, Tmx4, Sgsm1, Pgrmc1, Stk39, Vti1a, Gria3, Rragc, Ptbp2, Ak3, Ptpn9, Dbn1, Socs5, Foxo3, Rnf14, Mbnl1, Jph3, Extl2, Fam13a, Usp14, Gprc5b, Txndc12, Tmem57, Cyb5b, Rnf220, Asf1b, Ddx17, Slc25a46, Polr3g, Gpatch2, Tmem33, Camsap2, Atp2b1, Tmem178, Ndnf, Ankra2, Pdrg1, 1190002N15Rik, Abhd13, Zfp467, Sec62, Ttc9, Zfp619, Afap1, Gcc2, Draxin, Spag9, Fmnl2, Ap2b1, Klhl5, March8, Pdia6, Antxr2, Zcchc24, Dusp11, Slc37a3, Fbxl20, Usp36, Ttc4, Mvb12b, Dnajc6, Tppp, Ccnt2, 3110043O21Rik, Gpbp1, 1700012B15Rik, Lonrf3, Arl5a, Rap2a, Car12, Paqr4, Clasp2, Usp42, Golga1, Atg16l1, Kidins220, Myh10, Yipf6, Trappc6b, Mvp, Acap2, Ankrd17, Cacng7, Smarcd2, Pard6g, Vangl2, Trim9, Gopc, Dgcr8, Cadm3, Pds5b, Tbc1d14, Akap9, Inpp5f, Bbs4, Dnm3, Arrdc3, Epdr1, Ypel1, Tm9sf3, Grm7, Foxp1, Dnajc9, Jmjd1c, Fam73b, Ank2, Zfp91, Shroom2, Hlcs, Derl2, Fam57a, Ube3b, Hpcal4, Mtmr4, Zfp704, Glcci1, Mlc1, Cd99l2, Prpf8, Phf21a, Mical3, C2cd2, Rsrc2, Cblb, Daam1, Cpeb3, Prrt3, Kbtbd2, Dennd6a, Kmt2a, Gnptg, L3mbtl2, Rhbdl1, Vezt, Tom1l2, Hlf, 4933426M11Rik, Pacs2, Rasa1, Srek1, Spata13, Xkr6, Pcdh17, Golgb1, Cep120, Fam78b, Cdc42bpa, Ino80d, Camk1d, Sestd1, Zmynd8, 4932438A13Rik, Tnrc18, Vopp1, Eva1a, Mob1a, Ppp4r2, Luzp2, Arglu1, Psd3, Atg4d, Ago1, Nxt2, Eml6, Usp32, Pnma2, Phf20l1, Mb21d2, Gpr158, Rbm45, Lrrc55, Tspyl3, Podn, Wasf2, Stard13, Kat6a, Mllt6, Lgi2, Lsamp, Robo2, Caskin1, Luzp1, Nceh1, Zbtb39, Mdga2, Zhx3, Pitpnm3, Fnip2, Tmem67, Slc5a6, Dock1, Ksr2, Pcdhac1, Nefh, Lonrf2, Rbm33, Znrf3, Adcy1, Bdp1, Tnik |
| mmu-miR-327 | Up | Clk4, Mef2c, Ptprb, Slc2a4, Cntnap2, Fam168b, Cep68, Evi2b, Zmym5, Rasal2, Rab39, Pld5 |
| mmu-miR-207 | Up | Adcy6, Cplx2, Emp2, Gda, Itgam, Lpl, Nab1, Nrl, Pigr, Prlr, Slc22a12, Ubtf, Txnl4a, Preb, Sh3bgrl, Rab3c, Ascl4, Prr5l, Steap2, Crebrf, BC021785, Plcl1, Ntm, Gm4944, Prkag3, Dzank1, Oacyl |
| mmu-miR-466f-3p | Up | Adam9, Adcyap1r1, Akap2, Ap1g1, Xiap, Arf3, Zfhx3, Atf2, Atp7a, Pcdh15, Chic1, Bsn, Chek1, Cnr1, Cpd, Cry2, Drp2, E2f1, Efnb2, Eif2s1, Dmtn, Epha4, Ereg, Eya1, Fech, Gnb4, Grb2, Grik3, Hist1h1d, Foxq1, Hiat1, Hk2, Id2, Ids, Il17ra, Inpp5d, Jag2, Kcna4, Klra2, Hivep3, Loxl3, Mef2a, Mmp12, Mmp11, Mtf1, Nck2, Nfatc2, Nodal, Ints6, Npy1r, Slc11a2, Nrf1, Nrg3, Nrp2, Pappa, Piga, Pik3ca, Pik3r1, Prkcb, Plau, Prrx1, Ppargc1a, Pter, Ptp4a2, Ptprk, Rai1, Rgl1, Msr1, Cxcl5, Sin3a, Slc12a2, Smarca4, Spta1, Tcf4, Tcf7l2, Tcte1, Tll1, Tlr4, Tnfrsf11a, Trhr, Unc5c, Uty, Vegfa, Wfs1, Xk, Pcgf2, Zbtb7b, Ikzf2, Gtf2h2, Dnajb6, Rnasel, Sept3, Taf7, Ldb3, Cops7b, Azi2, Sytl4, Csnk1e, Prl5a1, Vps26a, Fbxl17, Sept11, Hif3a, B3gnt2, Diap2, Usp27×, Pitpnb, Pias1, Gsk3b, Akap10, Plag1, Gmeb1, Tbx20, Piwil2, Usp29, Cd200r1, Pard6b, Fign, Ms4a4b, Wtap, Ms4a4c, Gpr85, Mrps24, Dimt1, Haus2, Ccdc82, Atg10, Slc16a9, Slc25a46, Klhl13, Zfp169, Nacc2, Pdf, Golt1a, Rraga, Fndc1, Anln, Synpo2l, Phtf2, Casz1, Sash1, Mllt3, Tbc1d13, Rufy2, Prss22, Pgm2l1, Foxn3, Tmem25, Smug1, Mtfr2, Nup93, Cyb5r1, Ccpg1, Slc16a10, Ints8, Zfp444, Tmem161b, Zfp839, Appl1, Insig2, Larp1, Ddit4l, Rap2b, Ehhadh, Ubap2l, Ifitm7, Mdga1, Uhrf1bp1l, Dusp18, Arhgap12, Fam227a, Dcaf17, Sl×1b, Ppp1r14c, Abca6, Rtf1, Fam101b, B3gat1, Bcas1, Crebrf, Csrnp3, Cdk19, Clca2, Tbl1xr1, Tfcp2l1, Tdrd1, Pde4dip, Tas1r3, Mcam, Spock2, Arid4b, Hecw1, Ubac1, Lrrc19, Zfand2a, Zfp518b, Fbxl14, Adamts9, Dennd4a, Slc6a8, Dnm3, Unc5a, Ssr1, Mylk, Ston2, Trmt10a, Fam212b, Prr5, Lmx1a, Scn2a1, Erc1, Slc28a3, Rasa2, Pofut1, Asb13, Bbc3, Edaradd, Rwdd4a, Ash1l, Wfdc12, Ell2, Bzrap1, Prrg3, Ido2, Mkx, Alkbh1, Fam46a, Gabpb2, Armc2, Arhgef11, Tnrc6b, Tet2, Fam168b, BC003965, Tmprss13, Phactr2, Kctd11, Spag7, Evi2b, Rnf157, Nploc4, Stxbp6, Cep170b, Gxylt1, Tbc1d24, Cep76, Plcl1, Rabgap1, Cytip, Atp5g3, Mavs, Hnrnpa3, Bcl2l15, Slc6a17, Strip1, Cdc14a, Tmem201, Lin54, Oas1e, BC030336, Fus, Tpte, Psd3, Ankle1, Fhod1, Stard8, Ofd1, Zc3h12d, C2cd4c, Ric8b, Btnl9, Pfas, Fam160b2, Apol8, Rtp1, 9930021J03Rik, Zbtb34, Zbtb6, Lzts3, Dzank1, Zfp462, Klhl21, Rsbn1l, Ugt2b35, Ppm1k, Lonrf1, Cwf19l2, Zscan4c, Tbx22, Klf8, Atxn7, Oas3, Srgap3, Alkbh5, Greb1, Fam107a, Ctif, Nbeal1, Ss18l1, Lhfpl4, Fat3, Bpifc, Trim12c, Fndc3a, Hif1an, Itpripl2, A630001G21Rik, Zbtb39, Adrbk2, Hook3, Rnf152, Hist4h4, Ubn2, Fam169a, Sycp2, Ccdc169, Arl4c, Xpnpep3, Slfn5, Gfod1, Mast4, Skint7, Zfp516, Acot11, Taok3, Opcml, Gpd1l, Jhdm1d, Lin28b, Gm1587, Tbc1d22b, Arl14epl, Gse1, Mtx3, Zfp874b, Gm13476, Ociad2, Tmem178b, Fam169b, Scrt2, Zscan4d, Mast3, Zfp872, Zfp963, Zfp827, I830012O16Rik, AK010878 |
a
Validated target genes in miRTarBase database version 6.0. miR/miRNA, microRNA.