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5-Nitro-2-(3-phenylpropylamino) benzoic acid (NPPB) suppressed activation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway. (A) Protein expression of phosphorylated PI3K in human conjunctival fibroblasts (HConFs). (B) Protein expression of phosphorylated AKT in HConFs (*P<0.05 vs. control). DMSO, dimethyl sulfoxide; LUBI, lubiprostone.
