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. 2017 Dec 15;41(3):1529–1535. doi: 10.3892/ijmm.2017.3324

Figure 4.

Figure 4

miR-152 inhibits the ability of migration and invasion of ovarian cancer cells through ERBB3. (A and B) The number of invading cells was counted among SKOV3 and OVCAR3 cells transfected with scramble, miR-152, miR-152 and vector, or miR-152 and ERBB3 (P<0.05). (C and D) The migration assay was performed in SKOV3 and OVCAR3 cells transfected with scramble, miR-152, miR-152 and vector, or miR-152 and ERBB3. Magnification, ×200 (P<0.05). (E and F) The migration ability of SKOV3 and OVCAR3 cells that were transfected with scramble, miR-152, miR-152 and vector, or miR-152 and ERBB3 was measured by the wound healing assay at 1 and 3 days. (G) The gene network between miR-152 and ERBB3 was established in ovarian cancer. Blue nodes, miRs; yellow nodes, target genes.