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. 2017 Dec 20;41(3):1339–1348. doi: 10.3892/ijmm.2017.3334

Figure 1.

Figure 1

NO donor treatment inhibits the growth of U251 glioma cells. (A and B) Results of a CCK-8 assay indicated a concentration-dependent decrease in the viability of U251 glioma cells following exposure to 0–2 mM SNP or 0–500 µM GSNO for 36 h. (C and D) CCK-8 assay exhibited a reduction in cell viability at different time-points following SNP (2 mM) or GSNO (500 µM) treatment. Relative absorbance was normalized to the untreated group (0). *P<0.05 and ***P<0.001 compared with the untreated group (0). CCK-8, Cell Counting kit-8; GSNO, S-nitrosoglutathione; NO, nitric oxide; SNP, sodium nitroprusside.