Table 1.

Absolute amount and mean grams of each opioid prescribed over the study period, and the linear correlation between monthly total and time

Opioid	Total amount prescribed over study period, g	Mean g/month prescribed in England	Increase or decrease over time (Spearman’s r)
Buprenophine	92 500.3	2151.2	0.86
Codeine	27 922 622.7	649 363.3	0.89
Dihydrocodeine	22 190 184.3	516 050.8	−0.27
Fentanyl	2489.5	57.9	0.18
Methadone	1 931 295.7	44 913.8	−0.97
Morphine	4 835 679.9	112 457.7	0.75
Oxycodone	2 719 720.2	63 249.3	0.86
Tramadol	139 222 060.4	3 237 722.3	0.80