. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: J Trauma Acute Care Surg. 2018 Mar;84(3):473–482. doi: 10.1097/TA.0000000000001733

Table 2.

Short- and long-term outcomes stratified by CT-positive hDAI, predominant, and associated hDAI

Primary analysis CT-positive hDAI
	Crude			Adjusted
	OR (95% CI)	p	C-statistic	OR (95% CI)	p	C-statistic	H-L p
Discharge survival (n=361)	2.4 (1.3–4.2)	0.004	0.562	2.0 (0.99–3.9)^a	0.06	0.761	0.061
Favorable 3-month outcome (n=276)	2.1 (1.1–4.1)	0.03	0.563	1.7 (0.8–3.9)^a	0.19	0.789	0.961
Favorable 12-month outcome (n=255)	2.6 (1.4–5.1)	0.005	0.578	1.6 (0.7–3.4) ^b	0.27	0.758	0.586
Secondary analysis Predominant hDAI
	Crude			Adjusted
	OR (95% CI)	p	C-statistic	OR (95% CI)	p	C-statistic	H-L p
Discharge survival (n=327)	28.7 (3.9–211.9)	0.001	0.586	24.7 (3.2–192.6)^c	0.002	0.773	0.71
Favorable 3-month outcome (n=248)	4.2 (1.8–10.2)	0.001	0.575	2.3 (0.9–6.4)^b	0.1	0.761	0.313
Favorable 12-month outcome (n=230)	9.9 (3.4–28.5)	<.001	0.602	4.7 (1.5–15.2)^c	0.01	0.769	0.336
Associated hDAI
	Crude			Adjusted
	OR (95% CI)	p	C-statistic	OR (95% CI)	p	C-statistic	H-L p
Discharge survival (n=325)	0.8 (0.4–1.7)	0.58	0.509	1.12 (0.4–2.8)^d	0.96	0.772	0.072
Favorable 3-month outcome (n=253)	1.1 (0.4–2.8)	0.90	0.503	1.3 (0.4–4.1)^d	0.69	0.801	0.857
Favorable 12-month outcome (n=235)	0.8 (0.3–2.3)	0.71	0.509	0.5 (0.1–2.1)^e	0.25	0.851	0.836

Multivariable logistic regression models were adjusted for:

age, ISS, hypotension, Marshall CT classification;

age, ISS, and Marshall CT classification;

age, ISS, Marshall CT classification, and presence of contusion;

age, ISS, hypotension, and pupillary reactivity;

age, ISS, hypotension, pupillary reactivity and trauma cause. hDAI denotes hemorrhagic DAI; ISS, Injury Severity Score; H-L, Hosmer-Lemeshow; OR, odds ratio; CI, confidence interval. CT-hDAI negative patients served as reference group. A Hosmer-Lemeshow p-value of >0.05 indicates good model calibration.