Table 3.
ICU length-of-stay and ICU complications
| ICU complication | CT-hDAI-negative (n=291) |
CT-hDAI-positive (n=70) |
P | CT-hDAI-positive | |||
|---|---|---|---|---|---|---|---|
| Predominant (n=34) |
P | Associated (n=36) |
P | ||||
| ICU LOS (days) | 7 (2;15) | 16 (6; 24) | <.001 | 19 (11;24) | <.001 | 15 (2;24) | 0.09 |
| Herniation | 138 (47) | 20 (29) | 0.004 | 1 (3) | <.001 | 19 (56) | 0.35 |
| Brain edema requiring osmotherapy | 124 (43) | 33 (47) | 0.5 | 9 (25) | 0.04 | 24 (71) | 0.002 |
| Intracranial pressure crisis | 55 (57) | 25 (61) | 0.64 | 8 (47) | 0.46 | 17 (71) | 0.21 |
| Ischemic stroke | 29 (10) | 6 (9) | 0.83 | 0 (0) | 0.05 | 6 (18) | 0.17 |
| Seizure | 35 (12) | 3 (4) | 0.08 | 1 (3) | 0.15 | 2 (6) | 0.4 |
| Hyperglycemia | 235 (81) | 60 (86) | 0.34 | 28 (78) | 0.67 | 32 (94) | 0.06 |
| Pneumonia | 111 (38) | 38 (54) | 0.01 | 21 (58) | 0.02 | 17 (34) | 0.18 |
| Acute respiratory distress syndrome | 28 (6) | 11 (16) | 0.009 | 4 (11) | 0.28 | 7 (21) | 0.003 |
| Sepsis | 76 (28) | 29 (48) | 0.004 | 19 (58) | <0.001 | 10 (36) | 0.42 |
| Hypotension requiring vasopressors | 131 (45) | 38 (54) | 0.16 | 13 (36) | 0.31 | 25 (74) | 0.002 |
| Cardiac arrest in ICU | 24 (8) | 2 (3) | 0.19 | 0 (00 | 0.09 | 2 (6) | 1 |
| Fever | 180 (62) | 56 (80) | 0.004 | 33 (92) | <0.001 | 23 (68) | 0.51 |
| Acute renal failure | 27 (9) | 5 (7) | 0.81 | 1 (3) | 0.34 | 4 (12) | 0.55 |
P-values ≤0.02 (corrected for multiple [n=42] testing) were considered significant and are listed in bold. All comparisons were made against CT-hDAI-negative patients. Data are presented as median (IQR) or n (%). Data are complete for all included variables.