Table 2.
One-week outcomes among study participants who completed one-week follow-up
| Outcome variable | Naproxen + placebo (n=79) | Naproxen + orphenadrine (n=80) | Naproxen + methocarbamol (n=81) | Difference between orphenadrine vs. placebo (95%CI) | Difference between methocarbamol vs. placebo (95%CI) | Difference between orphenadrine vs. methocarbamol (95%CI) |
|---|---|---|---|---|---|---|
| Worst low back pain during previous 24 hours | 1% (−14, 16%) | 5% (−11, 20%) | 5% (−10, 20%) | |||
| Mild/none | 50 (66%) | 52 (67%) | 49 (61%) | |||
| Moderate/Severe | 26 (34%) | 26 (33%) | 31 (39%) | |||
| missing | 3 | 2 | 1 | |||
| Frequency of low back pain during previous 24 hours | 4% (−12, 20%)* | 7% (−8, 23%)* | 11% (−4, 27%)* | |||
| Never/rarely | 36 (47%) | 40 (51%) | 32 (40%) | |||
| Sometimes | 26 (34%) | 22 (28%) | 23 (29%) | |||
| Frequently/always | 14 (18%) | 16 (21%) | 25 (31%) | |||
| missing | 3 | 2 | 1 | |||
| Use of medication for low back pain during the 24 hours prior to one week follow-up | 4% (−12, 20%) | 7% (−8, 23%) | 11% (−4, 27) | |||
| No meds | 34 (45%) | 38 (49%) | 30 (38%) | |||
| Took meds | 42 (55%) | 40 (51%) | 50 (63%) | |||
| missing | 3 | 2 | 1 | |||
| Same medications during subsequent episode of low back pain1 | 0% (−15, 15%)** | 3% (−12, 18%)** | 3% (−12, 17%)** | |||
| Yes | 51 (68%) | 53 (68%) | 51 (65%) | |||
| No | 17 (23%) | 20 (26%) | 16 (21%) | |||
| Not sure | 7 (9%) | 5 (6%) | 11 (14%) | |||
| missing | 4 | 2 | 3 | |||
| Median days until usual activities (IQR)2 | 4 (2, 7) | 3 (2, >7) | 4 (2, >8) | 0.2 (−0.7, 1.0) | 0.3 (−0.6, 1.1) | 0.1 (−0.8, 1.0) |
| missing | 3 | 2 | 1 |
1
Participants were asked: “The next time you have back pain, do you want to take the same medications you’ve been taking this past week?”
2
Patients who had not yet recovered at the time of the one week phone call were categorized as >7 days.
*
Never/rarely versus sometimes/frequently/always
**
Yes versus no/not sure