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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Transplantation. 2018 Mar;102(3):e90–e100. doi: 10.1097/TP.0000000000002044

Figure 5. Immunofluorescent staining of graft infiltrating CD4+Foxp3+ T cells.

Figure 5

(A) Representative pictures of a cardiac allograft from sc28AT+hu5C8 group (MC9025, d118). Blue, DAPI nuclear staining; green, CD4; red, Foxp3. Several putative Tregs are identified by nuclear staining of Foxp3 surrounded by CD4 staining (white arrows). Original magnification, ×200 (left), × 600 (right). The right panel represents a magnification of the white rectangle indicated in the left panel. (B) Percentages of Foxp3+ cells among CD4+ lymphocytes in graft biopsies and functional (open boxes) or rejected (grey boxes) explanted cardiac allografts. Each dot represents the mean ± SEM of 2~7 fields from the same tissue specimen.