Table 2.
Comparison of study participants’ (total participants, n = 23) BMI, summary health state utility valuations for the EQ-5D-5L and the AQoL-8D, and EQ-VAS scores before and 3 months and 1 year after bariatric surgery, and sensitivity analyses for full completers (n = 9)
| Before surgery | 3 months after surgery | 1 year after surgery | Change in mean from 3 months to 1 year after surgery and ToS** (p ≤ 0.05) | Change in mean from before surgery to 1 year after surgery and ToS** (p ≤ 0.05) | |
|---|---|---|---|---|---|
| Years on public waiting list, mean (SD) | 6.5 (2.0)† | ||||
| BMI (kg/m2) Mean (SD) |
(n = 21) 49.3 (9.3)* |
(n = 21) 43.5 (7.2) |
(n = 22) 40.8 (7.0) |
−2.7 BMI points, p = 0.40 | −8.5 BMI points, p = 0.02** |
| %TWL, mean (SD) | NA | NA | 16% (7.1) | NA | 16% |
| %EWL, mean (SD) | NA | NA | 34% (14.9) | NA | 34% |
| MAUIs’ HSUVs and EQ-VAS scores (n = x) | |||||
| EQ-5D-5L | (n = 16) | (n = 19) | (n = 18) | ||
| Mean (SD) | 0.70 (0.25) | 0.80 (0.25) | 0.78 (0.25) | −0.02 utility points, p = 0.92 | +0.08 utility points, p = 0.25 |
| Median (IQR) | 0.73 (0.54–0.91) | 0.84 (0.59–0.86) | 0.86 (0.67–0.93) | ||
| AQoL-8D | (n = 15) | (n = 18) | (n = 17) | ||
| Mean (SD) | 0.51 (0.24) | 0.61 (0.24) | 0.67 (0.23) | +0.06 utility points, p = 0.66 | +0.16 utility points, p = 0.04** |
| Median (IQR) | 0.51 (0.29–0.78) | 0.58 (0.43–0.78) | 0.67 (0.48–0.86) | ||
| EQ-VAS | (n = 16) | (n = 19) | (n = 18) | ||
| Mean (SD) | 57 (25) | 67 (24) | 73 (19) | +6 points, p = 0.31 | +16 VAS score, p = 0.08 |
| Median (IQR) | 65 (34–73) | 65 (48–90) | 80 (56–90) | ||
| Subgroup analysis* (n = 9) | |||||
| BMI (kg/m2), mean (SD) | 47.6 (7.4) | 43.6 (6.1) | 39.6 (6.4) | 4.0 BMI points | −8.0 BMI points |
| %TWL, mean (SD) | NA | NA | 16.6% (7.3) | NA | 16.6% |
| %EWL, mean (SD) | NA | NA | 36.3% (15.8) | NA | 36.3% |
| EQ-5D-5L utility, mean (SD) | 0.69 (0.21) | 0.80 (0.15) | 0.73 (0.20) | −0.07 utility points, p = 0.52 | +0.04 utility points, p = 0.26 |
| AQoL-8D utility, mean (SD) | 0.45 (0.19) | 0.57 (0.21) | 0.60 (0.22) | +0.03 utility points, p = 0.07 | +0.15 utility points, p = 0.01** |
| EQ-VAS, mean (SD) | 59 (22) | 66 (22) | 67 (21) | +1 VAS score | + 8 VAS score, p = 0.18 |
BMI body mass index, EWL excess weight lost, HSUV health state utility valuation, IQR interquartile range, MAUI multi-attribute utility instrument, NA not applicable, SD standard deviation, ToS test of significance, TWL total weight lost, VAS visual analogue scale
† One long-term waitlisted patient's time on the waiting list not available
* Full-completers subgroup analysis before and 3 months and 1 year after bariatric surgery
** ToS Wilcoxon rank test (p ≤ 0.05)